Allele | Frequency | Treatment outcome (%) | ||
---|---|---|---|---|
Cured N = 72 | Failed N = 44 | P. value | ||
N = 116 | ||||
Pfcrt T 76 | 86 (74%) | 51 (71%) | 41 (93%) | |
Pfcrt K 76 | 11 (12%) | 11 (15%) | 0 (0%) | 0.003* |
T76+K76 | 19 (14%) | 10 (14%) | 9 (20%) | |
N = 116 | ||||
Pfmdr1 Y86 | 34 (29%) | 22 (31%) | 12 (27%) | |
Pfmdr1 N86 | 74 (64%) | 47 (65%) | 27 (61%) | n.s. |
Y86+N86 | 8 (7%) | 3 (4%) | 5 (11%) | |
N = 116 | ||||
Pfmdr1 F184 | 74 (64%) | 45 (63%) | 29(65%) | |
Pfmdr1 Y 184 | 35 (30%) | 24 (33%) | 11 (25%) | n.s. |
F184+Y184 | 7 (6%) | 3 (4%) | 4 (9%) | |
N = 116 | ||||
T76 + Y86 | 37 (32%) | 21 (29%) | 16 (36%) | |
K76 + N86 | 7 (6%) | 7 (10%) | 0 (0%) | 0.028* |
Mixed | 72 (62%) | 44 (61%) | 28 (64%) | |
N = 116 | ||||
T76 + F186 | 73 (63%) | 40 (56%) | 33 (75%) | |
K76 + Y184 | 2 (2%) | 2 (3%) | 0 (0%) | n.s. |
Mixed | 41 (35%) | 30 (42%) | 11 (25%) | |
N = 116 | ||||
T76+Y86+F184 | 35 (30%) | 19 (26%) | 16 (36%) | |
K76+N86+Y184 | 3 (3%) | 3 (4%) | 0 (0%) | n.s. |
Mixed | 78 (67%) | 50 (70%) | 28 (64%) |