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Table 4 Prevalence of mutant pfmdr1/pfcrt genes in Day 0 and recrudescence samples of patients that failed chloroquine treatment

From: Rapid detection of Pfcrt and Pfmdr1 mutations in Plasmodium falciparum isolates by FRET and in vivo response to chloroquine among children from Osogbo, Nigeria

 

Prevalence of alleles

 

Alleles

Day 0

Recrudescence

Mc Nemar P value

T76

44/44 (100%)

43/44 (98%)

1

Y86

17/44 (39%)

18/44 (41%)

1

F184

33/44 (75%)

27/44 (61%)

0.031*

T76+Y86

44/44 (100%)

43/44 (98%)

1

T76+F184

44/44 (100%)

43/44 (98%)

1

T76+Y86+F184

44/44 (100%)

44/44 (100%)

1

  1. Mixed infection is considered as mutant
  2. *Significant at P < 0.05