Table 3 Frequency of dhfr and dhps mutant alleles, genotypic study, Lainé refugee camp
Genotype Frequencies | n | % | 95% CI |
|---|---|---|---|
dhps (N = 114) | |||
wild type, | 8 | 7.0 | 3.1–13.6 |
single mutant 436 | 31 | 27.2 | 19.3–36.3 |
single mutant 437 | 38 | 33.3 | 24.8–42.8 |
double mutant 436–437 | 29 | 25.4 | 17.7–34.4 |
double mutant 437–540 | 8 | 7.0 | 3.1–13.6 |
dhfr (N = 148) | |||
wildtype | 20 | 13.5 | 8.4–20.1 |
double mutant 59–108 | 2 | 1.4 | 0.2–4.8 |
triple mutant 51–59–108 | 126 | 85.1 | 78.4–90.4 |
dhps and dhfr combined (N = 110) | |||
quintuple mutant: dhfr 51–59–108 &dhps 437–540 | 8 | 7.3 | 3.2–13.8 |
quintuple mutant: dhfr 51–59–108 & dhps 436–437 | 27 | 24.5 | 16.8–33.7 |
dhfr 51–59–108 & dhps single mutant | 54 | 49.1 | 39.4–58.8 |
Three or less mutations | 21 | 19.1 | 12.2–27.7 |