Table 4 Day 28 failure rates estimated by four methods – AS+SP treatment

Year

Method 1a

(per protocol)

Method 1b

Method 2a

(WHO 2001)

Method 2b

2002

21.7

13.2

15.4

29.8

[10.9–36.4]

[6.5–22.9]

[8.6–26.8]

[20.5–42.1]

2003

1.2

1.2

1.1

2.3

[0–6.6]

[0–6.4]

[0.2–7.8]

[0.6–8.8]

2003

33.3

25.3

27.3

59.5

[21.9–46.3]

[16.4–36.0]

[18.7–38.9]

[48.8–70.5]

2003

10.3

8.3

8.6

10.5

[3.9–21.2]

[3.1–17.3]

[4.0–18.2]

[5.4–19.9]

2003

7.9

6.8

6.8

8.0

[2.6–17.5]

[2.2–15.1]

[2.9–15.5]

[3.7–16.9]

2004

11.1

10.0

10.1

11.0

[4.9–20.7]

[4.4–18.8]

[5.2–19.2]

[5.9–20.2]

2004

2.3

2.0

2.0

11.8

[0–12.3]

[0–10.8]

[0.3–13.4]

[5.5–24.4]

2004

1.0

0.9

0.9

2.8

[0–5.5]

[0–5.2]

[0.1–6.5]

[0.9–8.5]