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Table 2 Mean percentage of lymphocyte subsets at presentation with acute non-complicated malaria, 4 weeks post-recovery and in healthy age-matched controls

From: Alterations on peripheral B cell subsets following an acute uncomplicated clinical malaria infection in children

Cell type

Acute

(A)

Recovery

(R)

Controls

(C)

Significance

mean (SEM)

percent

mean (SEM)

percent

mean (SEM)

percent

A vs.R

A vs.C

R vs.C

CD3+CD45+

56.9

(2.4)

54.3

(2.3)

52.7

(2.7)

0.37

0.27

0.67

CD19+CD45+

21.4

(2.1)

26.1

(1.7)

23.5

(2.8)

0.02

0.53

0.41

CD4+CD3+

34.8

(2.6)

36.0

(2.2)

29.4

(1.9)

0.64

0.14

0.04

CD8+CD3+

16.0

(2.5)

12.8

(1.2)

18.2

(0.8)

0.22

0.62

0.03

Naive 1

CD38-IgD+CD19+

23.7

(2.9)

29.3

(4.2)

38.2

(3.4)

0.03

0.00

0.12

Naive 2

CD38+IgD+CD19+

39.7

(3.8)

44.7

(4.4)

27.2

(4.4)

0.11

0.04

0.01

Memory 3

CD38+IgD-CD19+

22.7

(2.4)

14.4

(1.3)

14.2

(1.1)

0.00

0.01

0.91

Memory 4

CD38-IgD-CD19+

13.5

(1.4)

11.7

(1.3)

22.8

(2.6)

0.11

0.01

0.00

CD10+CD19+

24.6

(2.5)

29.0

(2.7)

21.2

(1.8)

0.04

0.31

0.04

  1. Sample size (n) was n = 15 for all Acute & Recovery outcomes except CD19+CD10+ (n = 12), and all Memory and Naive outcomes (n = 11). N = 11 for controls except for CD4 (n = 10), CD19+CD10+ (n = 9), CD19+CD27+ (n = 7), and CD8 (n = 5). Heterogeneity of variance assumptions were tested by the Levene statistic, and heterogeneous t-tests were utilized as needed. Significant differences are in bold.