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Table 1 Malaria treatments evaluated and their estimated efficacy

From: Plasmodium falciparum gametocyte dynamics in areas of different malaria endemicity

Treatment Group

Failure Rate (95% CI)1 (%)

Number of patients treated

 

Thailand

The Gambia

Tanzania

Artemisinin derivatives ± other drugs (A)

15 (14–17)

5324

9 (7–12)

1207

27 (20–36)

130

Antipyretics only (B)

  

33 (13–70)

32

Chloroquine (C)

 

42 (31–55)

120

62 (58–66)

1115

Halofantrine (D)

14 (11–18)

459

  

Mefloquine only (E)

32 (27–37)

1423

  

Quinine regimens (F)

22 (17–28)

311

 

75 (31–93)

8

Sulfadoxine-Pyrimethamine (G)

 

8 (5–11)

693

46 (29–67)

70

Sulfadoxine-Pyrimethamine + Chloroquine (H)

  

50 (21–87)

13

  1. 1 defined as recurrent parasitaemia within 42 days for Artemisinin derivatives (A) and Mefloquine (E) and 28 days for other treatments; estimated using Kaplan-Meier method.