Glucose-6-phosphate dehydrogenase (G6PD) mutations and haemoglobinuria syndrome in the Vietnamese population

Malaria Journal

Table 4 The frequency of factors that may contribute to the development of haemoglobinuria in the Vietnamese cohort

	Haemoglobinuria Kinh N = 82	Healthy Kinh N = 266	Healthy S'tieng N = 258
G6PD deficiency^a	48 (58.5)	23 (8.65)	36 (13.95)
Suspected malaria^b	34 (41.5)
Confirmed malaria^c	21(25.6)
Received anti-malarials^d	14 (17)
Harbour G6PD polymorphism^e	34 (41.5)	14 (0.05)	23 (0.09)
Harbour G6PD non-synonomous mutation	21(25.6)	6 (0.02)	14 (0.05)
Harbour G6PD published mutation	20 (24.4)	6 (0.02)	14 (0.05)

^adeficiency includes definite and probable G6PD deficiency
^bpatients that are smear positive for malaria and patients that have been on anti-malarial treatment
^cpatients that are smear positive for malaria only
^dpatients that have received either quinine or primaquine anti-malarial treatment
^eindividuals that harbour 1 or more polymorphism

ISSN: 1475-2875