First dose | Second dose | Third dose | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
15 μg MSP3 | 30 μg MSP3 | Engerix B | 15 μg MSP3 | 30 μg MSP3 | Engerix B | 15 μg MSP3 | 30 μg MSP3 | Engerix B | |||||||||||
N = 15 | N = 15 | N = 15 | N = 15 | N = 15 | N = 15 | N = 15 | N = 15 | N = 15 | |||||||||||
Symptom | Intensity | n | % | n | % | n | % | n | % | n | % | n | % | n | % | n | % | n | % |
Any | Overall | 8 | 53 | 10 | 67 | 7 | 47 | 12 | 80 | 6 | 40 | 6 | 40 | 9 | 60 | 12 | 80 | 9 | 60 |
Grade 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Pain | Overall | 3 | 20 | 2 | 13 | 1 | 6.7 | 1 | 6.7 | 1 | 6.7 | 1 | 6.7 | 0 | 0 | 1 | 6.7 | 2 | 13 |
Grade 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Swelling | Overall | 3 | 20 | 7 | 47 | 5 | 33 | 4 | 27 | 1 | 6.7 | 1 | 6.7 | 3 | 20 | 2 | 13 | 3 | 20 |
Grade 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Erythema | Overall | 0 | 0 | 2 | 13 | 1 | 6.7 | 1 | 6.7 | 1 | 6.7 | 1 | 6.7 | 1 | 6.7 | 0 | 0 | 2 | 13 |
Grade 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Induration | Overall | 8 | 53 | 10 | 67 | 6 | 40 | 12 | 80 | 7 | 47 | 6 | 40 | 8 | 53 | 12 | 80 | 8 | 53 |
Grade 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Pruritus | Overall | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.7 | 0 | 0 | 0 | 0 | 0 | 0 |
Grade 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |