Figure 1From: Sequence variation of PfEMP1-DBLα in association with rosette formation in Plasmodium falciparum isolates causing severe and uncomplicated malariaBinding ability of parasitized red blood cells to CD36 and ICAM-1 and rosette formation. The binding ability to CD36, ICAM-1Ref, ICAM-1Kilifi, ICAM-1S22/A (PRBCs/mm2) and rosetting rate (%) of isolates causing severe (black dot) and uncomplicated malaria (white dot). The mean number of PRBCs bound to each receptor is shown as a horizontal line. The percent of isolates causing severe (SM) and uncomplicated (UCM) malaria bound to each receptor were shown, CD36: 89% for SM and 78% for UCM; ICAM-1Ref: 48% for SM and 43% for UCM; ICAM-1Kilifi: 17% for SM and 21% for UCM; ICAM-1S22/A: 21% for SM and 17% for UCM; rosette formation: 79% for both SM and UCM.Back to article page