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Figure 2 | Malaria Journal

Figure 2

From: Sequence variation of PfEMP1-DBLα in association with rosette formation in Plasmodium falciparum isolates causing severe and uncomplicated malaria

Figure 2

Sequence groups of PfEMP1-DBLα domains from isolates causing severe and uncomplicated malaria. (A) Distribution of DBLα sequences of isolates causing severe (black dot) and uncomplicated (white dot) malaria in six sequence groups. DBLα sequences were divided into six sequence groups: sequence groups 1–3 contain two cysteine residues (cys2) and sequence groups 4 and 5 contain four cysteine residues (cys4). Sequence group 6 contains one, three, five, or six cysteines (cysX). Sequence groups 2 and 5 contain PoLV2*REY. Sequence group 1 contains PoLV1MFK*. The length of each distinct DBLα sequence within each sequence group is indicated; (B) The percent of isolates causing severe (black bar) and uncomplicated malaria (white bar) bound to each receptor.

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