Laboratory parameters | Treatments | D0 | D3 | D7 | D14 | 21 | 28 |
---|---|---|---|---|---|---|---|
Biochemistry | |||||||
Glucose mm/L | ANQ | 4.9 ± 0.9 | 5.5 ± 1.5 | 4.8 ± 0.8 | 4.5 ± 0.8 | 4.5 ± 0.5 | 5.0 ± 1.6 |
CQ+SP | 5.0 ± 1.0 | 5.5 ± 1.5 | 4.9 ± 0.8 | 4.5 ± 0.8 | 4.6 ± 0.5 | 5.2 ± 1.6 | |
Liver function | |||||||
*AST Units/L | ANQ | 43.2 ± 16.4 | 43.7 ± 22.6 | 41.6 ± 32.1 | 35.7 ± 17.9 | 31.0 ± 10.4 | 33.4 ± 10.2 |
CQ+SP | 44.2 ± 16.4 | 43.2 ± 16.4 | 42.2 ± 32.1 | 35.2 ± 17.9 | 31.0 ± 10.4 | 35.4 ± 10.2 | |
**ALT Units/L | ANQ | 44.1 ± 20.9 | 47.9 ± 24.9 | 53.0 ± 49.2 | 57.3 ± 33.7 | 36.4 ± 14.8 | 36.3 ± 21.4 |
CQ+SP | 46.1 ± 20.9 | 47.9 ± 24.9 | 54.0 ± 49.2 | 57.3 ± 34.0 | 36.4 ± 14.9 | 35.3 ± 21.4 | |
Bilirubin μm/L | ANQ | 19.4 ± 14.3 | 12.1 ± 8.8 | 10.7 ± 5.0 | 8.3 ± 1.5 | 8.8 ± 1.3 | 8.8 ± 1.9 |
CQ+SP | 18.4 ± 14.3 | 12.1 ± 8.8 | 10.6 ± 5.0 | 8.3 ± 1.5 | 8.0 ± 1.3 | 8.8 ± 2.0 | |
Alkaline phosphatase Units/L | ANQ | 75.9 ± 18.6 | 81.8 ± 24.7 | 87.5 ± 27.5 | 91.3 ± 29.5 | 80.5 ± 24.3 | 95.1 ± 38.1 |
CQ+SP | 76.4 ± 20.2 | 83.4 ± 23.1 | 86.1 ± 25.2 | 91.8 ± 28.4 | 77.6 ± 21.5 | 84.0 ± 39.0 | |
#GGT Units/L | ANQ | 39.5 ± 22.7 | 40.3 ± 24.8 | 34.7 ± 22.3 | 29.5 ± 13.5 | 16.8 ± 11.9 | 22.5 ± 7.4 |
CQ+SP | 40.5 ± 22.7 | 40.3 ± 24.8 | 34.7 ± 22.3 | 29.5 ± 13.5 | 16.3 ± 12.9 | 22.5 ± 7.5 | |
Renal function | |||||||
Creatinine μm/L | ANQ | 92.7 ± 19.4 | 91.8 ± 14.2 | 91.9 ± 18.1 | 87.9 ± 13.7 | 85.9 ± 10.9 | 79.3 ± 17.5 |
CQ+SP | 93.3 ± 19.3 | 92.8 ± 14.4 | 93.5 ± 19.1 | 88.9 ± 14.0 | 85.3 ± 11.5 | 80.4 ± 18.4 | |
Haematology | |||||||
Haemoglobin g/dl | ANQ | 10.8 ± 2.3 | 10.6 ± 1.8 | 10.4 ± 1.2 | 10.7 ± 1.0 | 11.1 ± 1.7 | 11.6 ± 1.4 |
CQ+SP | 11.0 ± 2.3 | 10.7 ± 1.9 | 10.5 ± 1.3 | 11.0 ± 0.9 | 11.1 ± 1.6 | 11.6 ± 1.5 | |
WBC ×109/L | ANQ | 5.2 ± 2.4 | 5.4 ± 1.7 | 5.5 ± 1.7 | 6.5 ± 2.5 | 6.6 ± 1.6 | 6.1 ± 1.7 |
CQ+SP | 5.4 ± 2.3 | 5.4 ± 1.6 | 5.8 ± 1.6 | 6.5 ± 2.3 | 6.6 ± 1.7 | 6.2 ± 1.8 | |
Electrolytes | |||||||
Sodium mm/L | ANQ | 134.9 ± 5.6 | 138.2 ± 3.4 | 135.6 ± 7.6 | 137.2 ± 2.6 | 136.5 ± 3.1 | 139.6 ± 5.4 |
CQ+SP | 135.9 ± 5.5 | 138.3 ± 3.3 | 136.1 ± 7.1 | 137.2 ± 2.4 | 136.4 ± 2.9 | 140.0 ± 5.5 | |
Potassium mm/L | ANQ | 3.8 ± 0.7 | 4.1 ± 1.1 | 4.2 ± 0.8 | 4.1 ± 0.7 | 3.9 ± 0.3 | 4.0 ± 0.7 |
CQ+SP | 3.8 ± 0.7 | 4.1 ± 0.7 | 4.2 ± 0.7 | 4.0 ± 0.7 | 4.0 ± 0.7 | 4.1 ± 1.0 |