Shift in epitope dominance of IgM and IgG responses to Plasmodium falciparum MSP1 block 4

Malaria Journal

Table 1 Pair-wise correlation of IgM and IgG MFI values for block 4 peptides and blocks 16-17*

Antigen Pair		Colombia		Papua New Guinea		Cameroon
IgM		r	P	r	P	r	P
4-1	4-2	0.966	< .0001	0.9888	< .0001	0.7644	< .0001
4-1	4-3	0.9663	< .0001	0.7354	< .0001	0.3792	0.001
4-1	4-4	0.9876	< .0001	0.9963	< .0001	0.6942	< .0001
4-2	4-3	0.9877	< .0001	0.8133	< .0001	0.9263	< .0001
4-2	4-4	0.9829	< .0001	0.9859	< .0001	0.659	< .0001
4-3	4-4	0.9764	< .0001	0.7318	< .0001	0.318	0.0065
IgG		r	P	r	P	r	P
4-1	4-2	0.0888	0.3543	-0.1114	0.5507	0.1737	0.1699
4-1	4-3	0.2389	0.0116	0.8043	< .0001	0.6795	< .0001
4-1	4-4	0.0583	0.5432	-0.1443	0.4386	0.3889	0.0015
4-2	4-3	0.0253	0.7918	-0.036	0.8475	0.1993	0.1143
4-2	4-4	0.7882	< .0001	0.8756	< .0001	0.2502	0.0462
4-3	4-4	0.0031	0.9745	-0.105	0.5739	0.0976	0.443

*Pearson's product moment correlation coefficient (r) and corresponding P values. Significant r values are highlighted in bold print(P < 0.05).

ISSN: 1475-2875