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Table 1 Clinical and parasitological treatment failures

From: Different mutation patterns of Plasmodium falciparum among patients in Jimma University Hospital, Ethiopia

PCR-corrected failure rates*

AL

Q

AP

Number of patients with recrudescence/total number of patients (day)

1/30 (70)**

4/35 (24, 28, 28, 40)

2/32(28, 28)

Drug resistance associated polymorphisms

1. pfserca gene

2. pfmdr codon 86N

1. pfmdr codon 86N

1. cytb gene codon 268

2. dhfr triple mutation (51I+59R+108N)

3. dhfr codon A16V

Polymorphisms in recrudescent samples n (%)

1. 0 (0)

2. 0 (0)

   1. 0 (0)

1. 0 (0)

2. 2 (100)

3. 1 (50)

  1. *P. falciparum: Genotyping by PCR and RFLP patterns of the msp-1 and msp-2 gene
  2. **Possible Recrudescence