Skip to main content

Table 3 Summary of studies evaluating malaria diagnostic accuracy of the Coulter GEN·S and LH 750 analysers.

From: Automated haematology analysis to diagnose malaria

First author, year and country

Number of participants and diagnoses

Standard reference test

Blinding

Malaria factor

Sensitivity %

Specificity %

Fourcade, 2004, France and Spain [49]

Total: 89, P. falciparum: 28, P. vivax: 4

Microscopy, HRP2+ pan-malarial antigen (Binax Now)

-

5.1

82.5

96.9

Briggs, 2006, South Africa and England [48]

Total: 1354, healthy: 1079, febrile: 135, HIV infected: 51, P. falciparum: 120, P. vivax: 11, P. ovale: 7, P. malariae: 1, mixed P. falciparum and P. vivax: 1

Microscopy, QBC, HRP2+ pan-malarial antigen (Binax Now), Pf HRP2 (MAKROmed), P-LDH (optiMAL)

-

3.7

98

94

Kang, 2008, South Korea [66]*

Total: 395, P. vivax: 68

Microscopy

**

4.57

81.8

72.3

  1. *Article in Korean, only abstract in English. **Could not be assessed.