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Table 2 Comparison of proportion of multiple alleles and mean allele counts in the baseline and post-ITN parasite populations

From: Effects of transmission reduction by insecticide-treated bed nets (ITNs) on parasite genetics population structure: I. The genetic diversity of Plasmodium falciparum parasites by microsatellite markers in western Kenya

Locus

Baseline population (n = 69)

Post-ITN population (n = 74)

p- value < 0.006*

 

% MA

MAC ± SE

% MA

MAC ± SE

% MA*

MAC*

Poly-α

64

2.12 ± 0.13

72

2.40 ± 0.14

0.289

0.264

Pfg377

30

1.36 ± 0.07

53

1.62 ± 0.09

0.002

0.008

PfPK2

85

2.94 ± 0.17

50

1.74 ± 0.11

0.021

0.001

ADL

45

1.62 ± 0.10

50

1.54 ± 0.07

0.479

0.918

EBP

57

1.75 ± 0.10

61

2.10 ± 0.14

0.566

0.128

P195

43

1.48 ± 0.08

48

1.62 ± 0.09

0.570

0.400

TAA60

51

1.77 ± 0.13

59

2.04 ± 0.12

0.044

0.046

TAA109

75

2.28 ± 0.14

76

2.23 ± 0.12

0.990

0.810

Overall

94.2†

3.4 ± 0.15‡

95.9 †

3.1 ± 0.12‡

0.830

0.178

  1. % MA is the proportion of infections with more than one allele in each locus. MAC denotes the mean allele count and the respective standard error (SE) at each locus. The † marks the overall proportion of infections with at least two alleles while ‡ marks the overall mean of the highest number of allele count detected by any of the 8 microsatellites. The % MA* and MAC* show p-values for differences in proportion of multiple alleles and mean allele counts between the two parasite populations. Numbers highlighted in bold show significant differences at p < 0.0063 (with Bonferroni correction) for individual loci.