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Figure 4 | Malaria Journal

Figure 4

From: Uptake of purines in Plasmodium falciparum-infected human erythrocytes is mostly mediated by the human Equilibrative Nucleoside Transporter and the human Facilitative Nucleobase Transporter

Figure 4

Adenine transport in uninfected human erythrocyte. A, Uptake of 0.25 μM [3H]-adenine into uninfected human erythrocytes in the presence (open circles) or absence (solid squares) of 1 mM unlabelled adenine, expressed as pmol(107 cells)-1. Experiment shown is representative of four independent experiments conducted in triplicate. B and C, Uptake of 1 μM [3H]-adenine, expressed as pmol(107 cells)-1s-1, by uninfected human erythrocytes over 5 s, in the presence or absence of various concentrations of unlabelled adenine (solid squares), NPPB (Frame B, open circles) or furosemide (Frame C, open circles). Experiments shown are representative of four independent experiments and conducted in triplicate. Bars represent SEM.

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