From: Factors contributing to delay in parasite clearance in uncomplicated falciparum malaria in children
Variables | Number enrolled | PC >2 d | Crude OR (95% CI) | P Value | Adjusted OR (95% CI) | P Value |
---|---|---|---|---|---|---|
Age (years) | Â | Â | Â | Â | Â | Â |
   >2 | 2446 | 1076 | 1 |  | 1 |  |
   ≤ 2 | 267 | 140 | 1.40 (1.09 -1.80) | 0.008 | 2.13 (1.44 -3.15) | <0.0001 |
Gender | Â | Â | Â | Â | Â | Â |
   Female | 1342 | 607 | 1 |  |  |  |
   Male | 1240 | 557 | 0.98 (0.84 -1.15) | 0.870 | - | - |
Fever* | Â | Â | Â | Â | Â | Â |
   Absent | 686 | 252 | 1 |  | 1 |  |
   Present | 1743 | 842 | 1.6 (1.34 -1.93) | <0.0001 | 1.33 (1.04-1.69) | 0.019 |
Duration of illness (d) | Â | Â | Â | Â | Â | Â |
   ≤ 3 | 2085 | 926 | 1 |  |  |  |
   > 3 | 521 | 246 | 1.12 (0.90 - 1.30) | 0.225 | - | - |
Haematocrit (%) | Â | Â | Â | Â | Â | Â |
   ≥ 30 | 614 | 182 | 1 |  |  |  |
   <30 | 380 | 114 | 1.01 (0.76 - 1.34) | 0.904 | - | - |
Parasitaemia (/μl blood) |  |  |  |  |  |  |
   ≤ 50,000 | 1607 | 634 | 1 |  | 1 |  |
   > 50,000 | 1145 | 603 | 1.70 (1.46 -1.99) | <0.0001 | 2.21 (1.77 - 2.75) | < 0.0001 |
Gametocytaemia | Â | Â | Â | Â | Â | Â |
   Absent | 2086 | 896 | 1 |  |  |  |
   Present | 232 | 90 | 0.84 (0.63 - 1.10) | 0.224 | - | - |
Vomiting | Â | Â | Â | Â | Â | Â |
   No | 1005 | 519 | 1 |  | 1 |  |
   Yes | 665 | 387 | 1.34 (1.07-1.58) | 0.009 | 1.21 (0.90-1.51) | 0.089 |
Hepatomegaly | Â | Â | Â | Â | Â | Â |
   Absent | 471 | 237 | 1 |  |  |  |
   Present | 798 | 430 | 1.54 (0.91 - 1.44) | 0.219 | - | - |
Year of enrolment | Â | Â | Â | Â | Â | Â |
   2000 onward | 2165 | 872 | 1 |  | 1 |  |
   Before or 1999 | 587 | 365 | 2.43 (2.02 - 2.94) | 0.0.00 | 1.55 (1.22-1.96) | < 0.0001 |