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Table 3 Predictors of delay in parasite clearance at presentation in children with acute falciparum malaria

From: Factors contributing to delay in parasite clearance in uncomplicated falciparum malaria in children

Variables

Number enrolled

PC

>2 d

Crude OR

(95% CI)

P

Value

Adjusted OR (95% CI)

P

Value

Age (years)

      

   >2

2446

1076

1

 

1

 

   ≤ 2

267

140

1.40 (1.09 -1.80)

0.008

2.13 (1.44 -3.15)

<0.0001

Gender

      

   Female

1342

607

1

   

   Male

1240

557

0.98 (0.84 -1.15)

0.870

-

-

Fever*

      

   Absent

686

252

1

 

1

 

   Present

1743

842

1.6 (1.34 -1.93)

<0.0001

1.33 (1.04-1.69)

0.019

Duration of illness (d)

      

   ≤ 3

2085

926

1

   

   > 3

521

246

1.12 (0.90 - 1.30)

0.225

-

-

Haematocrit (%)

      

   ≥ 30

614

182

1

   

   <30

380

114

1.01 (0.76 - 1.34)

0.904

-

-

Parasitaemia (/μl blood)

      

   ≤ 50,000

1607

634

1

 

1

 

   > 50,000

1145

603

1.70 (1.46 -1.99)

<0.0001

2.21 (1.77 - 2.75)

< 0.0001

Gametocytaemia

      

   Absent

2086

896

1

   

   Present

232

90

0.84 (0.63 - 1.10)

0.224

-

-

Vomiting

      

   No

1005

519

1

 

1

 

   Yes

665

387

1.34 (1.07-1.58)

0.009

1.21 (0.90-1.51)

0.089

Hepatomegaly

      

   Absent

471

237

1

   

   Present

798

430

1.54 (0.91 - 1.44)

0.219

-

-

Year of enrolment

      

   2000 onward

2165

872

1

 

1

 

   Before or 1999

587

365

2.43 (2.02 - 2.94)

0.0.00

1.55 (1.22-1.96)

< 0.0001

  1. CI, confidence interval; OR, odd ratio; PC, parasite clearance, *Body temperature ≥ 37.5°C