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Table 1 Characteristics of 913 infants selected from Asembo Bay Cohort Project

From: Polymorphisms in genes of interleukin 12 and its receptors and their association with protection against severe malarial anaemia in children in western Kenya

 

Subjects, no. of any incidence (%)a

 

Total

SAb

P

HDPc

P

SAPd

P

SMAe

P f

Sex

         

   Male

441

213 (48)

.03

357 (81)

.33

192 (44)

.03

77 (18)

.33

   Female

472

194 (41)

 

370 (78)

 

172 (36)

 

71 (15)

 

Sickle cell type

         

   AS

147

51 (35)

.01

112 (77)

.02

46 (31)

.03

13 (9)

.008

   AA

656

316 (48)

 

547 (83)

 

280 (43)

 

122 (17)

 

   SS

25

13 (52)

 

17 (68)

 

12 (48)

 

2 (8)

 

Anti-malarial use

         

   Yes

786

371 (47)

< .0001

661 (84)

< .0001

331 (42)

.0006

137 (17)

.01

   No

127

36 (28)

 

66 (52)

 

33 (26)

 

11 (9)

 

Placental blood parasitaemia

         

   Yes

210

84 (40)

.05

161 (77)

.11

76 (36)

.09

35 (17)

.93

   No

481

232 (48)

 

394 (82)

 

207 (43)

 

79 (16)

 

Maternal peripheral parasitaemia

         

   Yes

296

121 (41)

0.1

230 (78)

.25

109 (37)

.17

57 (19)

.11

   No

598

279 (47)

 

484 (81)

 

249 (42)

 

90 (15)

 

Birth weight < 2500 g or gestation age < 37 weeks

         

   Yes

82

35 (43)

.58

59 (72)

.03

31 (38)

.54

15 (18)

.58

   No

636

292 (46)

 

522 (82)

 

263 (41)

 

101 (16)

 

Low birth weight (< 2500 g)

         

   Yes

71

29 (41)

.41

51 (72)

.05

25 (35)

.31

13 (18)

.61

   No

651

299 (46)

 

532 (82)

 

270 (41)

 

104 (89)

 

Pre-term birth (< 37 weeks gestation)

         

   Yes

29

11 (38)

.44

18 (62)

.01

10 (35)

.51

3 (10)

.37

   No

846

382 (45)

 

685 (81)

 

343 (41)

 

141 (17)

 
  1. NOTE
  2. a Any incidence: at least once; displayed are frequency counts (percentage).
  3. b SA: Severe anaemia (Hb < 6 g/dL).
  4. c HDP: High density parasitaemia (> 10,000 P. falciparum parasites/μl).
  5. d SAP: Severe anaemia with any density parasitaemia (Hb < 6 g/dL with any detectable P. falciparum parasitaemia).
  6. e SMA: Severe malaria anaemia Hb < 6 g/d Land > 10,000 P. falciparum parasites/μl)
  7. f Chi-square p-values.