Skip to main content
Figure 1 | Malaria Journal

Figure 1

From: Splenic CD11c(+) cells derived from semi-immune mice protect naïve mice against experimental cerebral malaria

Figure 1

The proportion of B220(+)CD11c(+)low cells was higher and the size of CD11c(+)hi cells was enhanced on day 7 post-infection in semi-immune mice challenged three months after the third exposure to malaria. (A) Median percentages of splenic CD4(+), CD8(+) and CD11c(+) cells on day 7 post-infection (±interquartile range) (n = 6-7 mice/group). (B) Median percentages and number of splenic B220(+)CD11c(+)low cells and B220(−)CD11c(+)hi cells on day 7 post-infection (±interquartile range) (n = 4 mice/group). Plots show the gating strategy and data for representatives of these cells on day 7 post-infection in semi-immune and naïve mice. (C) Relative median size of splenic CD11c(+)hi cells on day 7 post-infection (±interquartile range) (n = 4 mice/group). Representative histograms regarding the size of CD11c(+)hi cells in semi-immune (black) and naïve (red) mice on day 0 and day 7 post-infection are shown. Data are pooled from two independent experiments (A, B) or representative of two independent experiments (C). *P < 0.05, Mann–Whitney U test.

Back to article page