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Table 4 Haplotypes frequencies of IL10A in malaria (+) and malaria (−) groups

From: IL10A genotypic association with decreased IL-10 circulating levels in malaria infected individuals from endemic area of the Brazilian Amazon

Haplotypes frequencies

 

−592

−819

−1082

Malaria (+)

Malaria (−)

OR (95% CI)

* P value

Hap1

C

C

G

0.3257

0.37

1.00

-

Hap2

A

T

A

0.3805

0.3056

0.85 (0.40 – 1.77)

0.66

Hap3

C

C

A

0.0989

0.2486

0.36 (0.14 – 0.93)

0.036

Hap4

A

T

G

0.1948

0.0759

3.83 (1.40 – 10.45)

0.009

  1. -592/-819/-1082: Positions of polymorphisms in the promoter region of the interleukin 10 gene; OR (95% CI), calculating odds ratios with confidence interval (CI) of 95%; *Analysis by calculating EMV via EM algorithm using a logistic regression model.