Figure 4

Binding of field isolates to human endothelial cells as well as parasites pre-selected for endothelial cytoadhesion can be quantified. Seven different parasite lines were tested for binding to hBMEC and hAEC. A) Bar graph showing binding to hBMEC. Binding to hBMEC is normalised to the binding of 3D7 SM [18] parasites not pre-selected to endothelial binding. B) Bar graph showing binding to hAEC. Binding to hAEC is normalised to the binding of 3D7 SM [18] parasites not pre-selected to endothelial binding. Bar show the mean fold change and error bars show standard deviation.