PR | HR | QT | QTcB | QTcF | 95% *Confidence interval | *P-value | |
---|---|---|---|---|---|---|---|
Visit | |||||||
Day 1 (baseline) | 134. 2 | 104. 6 | 331. 9 | 429. 6 | 393. 3 | - | - |
Day 3 pre-dose 3 | 138. 3 | 92. 5 | 355. 4 | 434. 2 | 411. 2 | - | - |
Day 3 post-dose 3 | 140. 5 | 91. 6 | 366. 1 | 444. 1 | 415. 8 | - | - |
Day 7 | 137. 6 | 94. 2 | 346. 2 | 428. 2 | 398. 6 | - | - |
Δ Days 1 to 3 pre-dose | 4. 1 | −12. 1 | 23. 5 | 4. 6 | 17. 9 | 16 ,19 | <0. 001 |
Δ Days 1 to 3 post-dose | 6. 3 | −13. 1 | 34. 2 | 14. 6 | 22. 5 | 21,24 | <0. 001 |
Δ Days 1 to 7 | 3. 3 | −10. 3 | 14. 2 | -. 31 | 5. 3 | 4,7 | <0. 001 |