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Table 1 Clinical, parasitological and plasma cytokine levels of pregnant women

From: Nrf2-driven CD36 and HO-1 gene expression in circulating monocytes correlates with favourable clinical outcome in pregnancy-associated malaria

 

All (N = 25)

BW ≤2.5 kg (N = 5)

P ≥1 % (N = 8)

pP ≥1 % (N = 10)

Age (years)

25 (22–30)

25 (21–37)

22 (20–23)**

23 (22–27)

Gravidity

2.0 (2.0–3.5)

2.0 (2.0–6.0)

2.0 (1.0–2.0)*

2.0 (1.0–3.0)

Birth weight (kg)

2.8 (2.5–3.1)

2.0 (1.7–2.2)**

2.8 (2.6–3.2)

2.9 (2.8–3.4)

P (%)

0.05 (0.01–3.5)

0.03 (0.02–2.9)

6.0 (4.1–10.8)***

2.2 (0.03–8.7)

pP (%)

1.0 (0.07–13.5)

0.1 (0.06–12.4)

28.0 (3.7–59.0)*

21.5 (10.0–63.0)***

TNF (pg/mL)

0 (0–0.8)

0 (0–12.2)

0 (0–0.1)

0 (0–0.6)

IL-10 (pg/mL)

0 (0–186)

111 (14–226)

628 (506–891)***

308 (12–732)

  1. Data are presented in medians (interquartile range)
  2. Data were compared according to the clinical criteria defined (BW ≤2.5 kg versus BW >2.5 kg, P <1 % versus P ≥1 %, pP <1 % versus pP ≥1 %) by Mann–Whitney U-test
  3. P peripheral parasitaemia, pP placental parasitaemia
  4. * P < 0.05, ** P < 0.005, *** P < 0.0005