Fig. 2

Sequence polymorphism of the PvAMA-1 in Korean Plasmodium vivax isolates. The amino acid sequences of Korean PvAMA-1 were compared to the Sal I sequence (AF063138). Identical amino acid residues are indicated by dots. The 44 non-synonymous SNPs identified in 66 Korean PvAMA-1 resulted in 44 amino acid changes, all of which were dimorphic. The amino acid changes were not evenly distributed in each PvAMA-1 haplotype, but the sequences clustered into an individual cluster share common amino acid changes. The conserved amino acid changes identified in all sequences in the corresponding cluster were represented as red and amino acid changes identified in at least one sequence in the corresponding cluster were marked as black. Red asterisks indicate the commonly identified amino acid changes in all Korean PvAMA-1. The total number of isolates for each cluster is listed in the right panel