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Table 1 Description of drug information sources used to determine anti-malarial and malaria exposure status

From: Risks of miscarriage and inadvertent exposure to artemisinin derivatives in the first trimester of pregnancy: a prospective cohort study in western Kenya

Approach

Format

Drug information available

EMEP self-report

Retrospective self-report of illness and medication used since the beginning of the pregnancy collected at every ANC visit and at pregnancy outcome follow-up visit. A general open question about any drug use as well as a directed question for specific anti-malarials were included as using medication/indication-specific questions have been shown to improve accuracy. Photographs of all anti-malarial drugs found in the study area were used to facilitate recognition of drug names. A calendar marking public holidays and school closures was also used to enhance recall of dates

Drug name

Drug start date

Duration

Number of tablets per day

Indication and indication diagnosis

Drug source

Lwak-OPD records

Prospective documentation by health facility clinic staff of diagnosis and treatment prescribed at outpatient department (OPD) whenever a PBIDS participant sought care at Lwak Hospital for an infectious syndrome

Date of visit

Diagnosis

Prescribed treatment

PBIDS weekly and twice-monthly home visits

Self-report of symptoms, health-seeking behaviour and medication. This information was collected continuously on a weekly (from 5 January, 2010 to 26 May, 2011) and then twice-monthly basis (27 May, 2011 onwards). The same visual aids as described above were used for recall of drug intake

Date of visit

Symptoms in previous week/2 weeks

Treatment taken for the symptoms including drug name

If and where care was sought

  1. ANC antenatal care, EMEP evaluation of medications used in early pregnancy study, Lwak OPD Lwak hospital out-patient department, PBIDS population-based infectious disease surveillance