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Fig. 4 | Malaria Journal

Fig. 4

From: Identifying rapidly parasiticidal anti-malarial drugs using a simple and reliable in vitro parasite viability fast assay

Fig. 4

Determination of killing rate profile for different classical anti-malarial drugs. Plasmodium falciparum viability time-course profile for artesunate, chloroquine, atovaquone, and pyrimethamine at 10 × IC50. Fast-acting anti-malarial drugs (artesunate and chloroquine) can be readily distinguished from moderate or slow-acting compounds (pyrimethamine and atovaquone). The number of viable infected erythrocytes was normalized using the number of untreated parasites. Error bars represent SEM for 4–9 replicates

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