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Fig. 5 | Malaria Journal

Fig. 5

From: Identifying rapidly parasiticidal anti-malarial drugs using a simple and reliable in vitro parasite viability fast assay

Fig. 5

Two-time point viability analysis using an abbreviated procedure. Plasmodium falciparum cultures were treated with indicated drugs and parasites sampled after 24 and 48 h. Medium-throughput conditions allowed discrimination of fast-acting profiles of pyronaridine, halofantrine, lumefantrine, piperaquine and mefloquine from the azithromycin anti-malarial profile, with parasite killing only in the second generation. The number of viable infected erythrocytes was normalized using the number of untreated parasites. Error bars represent SEM for 4–9 replicates

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