Table 3 Parasitemia suppression versus untreated controls and survival in mice infected with Plasmodium berghei after oral administration of plant extracts for four days
From: In vitro and in vivo anti-malarial activity of plants from the Brazilian Amazon
Plant | Part | Extract | Dose (mg/kg/day) | % parasite ± SD (% suppression) | Avg. survival ± SD (days) | |
|---|---|---|---|---|---|---|
Day 5 | Day 7 | |||||
Andropogon leucostachyus | Aerial part | MeOH | 250 | 0.49 ± 0.10 (71) | 1.12 ± 0.07 (48) | 19 ± 2 |
Croton cajucara RV | Leaf | CHCl3 | 250 | 1.4 ± 0.27 (19) | 2.2 ± 0.15 (0) | 23 ± 3 |
Xylopia amazonica | Leaf | CHCl3 | 250 | 0.82 ± 0.22 (52) | 1.87 ± 0.26 (11) | 20 ± 2 |
Controls |  | Chloroquine diphosphate | 10 | 0.15 ± 0.04 (91) | 0.14 ± 0.04 (93) | 31 ± 4 |
Vehicle (Blank) |  | 1.74 ± 0.21 | 2.12 ± 0.31 | 22 ± 1 | ||