Table 5 Estimated country-level impact of RTS,S vaccination
Country | Number of vaccinees | Median (95 % CI) | |||
|---|---|---|---|---|---|
Clinical malaria cases averted | Severe malaria cases averted | Malaria hospitalizations averted | Malaria deaths averted | ||
Vaccination at 6, 10 and 14 weeks | |||||
Burkina Faso | 673,961 | 234,951 (2090, 477,517) | 4182 (−6846, 14,515) | 3474 (−5688, 12,059) | 1092 (−1788, 3,790) |
Democratic Republic of Congo | 2,177,255 | 590,733 (77,960, 1,114,625) | 13, 943 (−22,087, 41,080) | 11, 583 (−18,349, 34,128) | 3641 (−5767, 10,727) |
Ghana | 739,857 | 180,785 (17,756, 344,188) | 4080 (−8121, 11,908) | 3389 (−6747, 9893) | 1065 (−2121, 3109) |
Kenya | 1,423,439 | 96,415 (12,032, 189,548) | 2805 (−6042, 9841) | 2330 (−5020, 8176) | 732 (−1578, 2570) |
Nigeria | 3,641,124 | 1,137,914 (106,434, 2,194,118) | 25,223 (−41,239, 77,330) | 20,955 (−34,261, 64,243) | 6586 (−10,768, 20,192) |
Tanzania | 1,879,173 | 255,645 (37,085, 478,220) | 6484 (−13,984, 19,374) | 5387 (−11,618, 16,096) | 1693 (−3,652, 5059) |
Senegal | 469,921 | 36,048 (7275, 67,343) | 1477 (−3337, 4803) | 1227 (−2772, 3990) | 386 (−871, 1254) |
Uganda | 1,462,572 | 411,047 (11,695, 819,896) | 7480 (−14,269, 24,160) | 6214 (−11,854, 20,071) | 1953 (−3726, 6309) |
42 countries in sub-Saharan Africa | 25,210,481 | 5,004,489 (474,867, 9,684,160) | 118,736 (−214,795, 372,995) | 98,642 (−178,445, 309,873) | 31,004 (−56,087, 97,396) |
Vaccination at 6, 7.5 and 9 months | |||||
Burkina Faso | 488,861 | 562,795 (327,910, 669,793) | 9985 (−54, 19,791) | 8295 (−45, 16,441) | 2607 (−14, 5168) |
Democratic Republic of Congo | 1,551,474 | 1,414,342 (923,277, 1,657,736) | 28,922 (1270, 54,286) | 24,028 (1,055, 45,099) | 7552 (332, 14,175) |
Ghana | 541,400 | 468,774 (323,528, 549,868) | 8254 (82, 15,470) | 6857 (69, 12,852) | 2155 (22, 4040) |
Kenya | 1,041,584 | 260,446 (189,489, 307,495) | 5,641 (−636, 11,453) | 4,686 (−528, 9,515) | 1473 (−166, 2991) |
Nigeria | 2,624,558 | 2,749,346 (1,748,642, 3,234,411) | 54,546 (1758, 103,606) | 45,315 (1460, 86,073) | 14,243 (459, 27,054) |
Tanzania | 1,382,820 | 693,506 (515,124, 811,055) | 12,453 (−451, 23,670) | 10,346 (−375, 19,665) | 3252 (−118, 6181) |
Senegal | 344,479 | 101,544 (80,459, 118,862) | 2741 (−315, 5441) | 2277 (−262, 4520) | 716 (−82, 1421) |
Uganda | 1,072,051 | 1,038,791 (657,896, 1,229,031) | 16,671 (−72, 32,293) | 13,850 (−60, 26,828) | 4353 (−19, 8432) |
42 countries in sub-Saharan Africa | 18,313,808 | 12,484,309 (8,242,412, 14,696,728) | 250,448 (−433, 481,819) | 208,064 (−359, 400,280) | 65,397 (−113, 125,813) |