Fig. 2
From: Recent advances in the biology and drug targeting of malaria parasite aminoacyl-tRNA synthetases
Cellular distribution of 36 malaria parasite aminoacyl-tRNA synthetases (aaRSs). All 36 aaRSs are encoded by the nuclear genome. 16 aaRSs are exclusively present in cytoplasm (Cyto aaRSs) of parasite and 15 are exclusive to the apicoplast (Api aaRSs). Four aaRSs; AlaRS, ThrRS, GlyRS and CysRS are shared by both apicoplast and the cytoplasm by mechanism of dual localization (denoted as Dual aaRSs). A unique amidotransferase (GatAB) provides the glutamine charged cognate tRNA in the apicoplast. Mitochondrion contain only one enzymatically active aaRS; PheRS (mFRS). Mitochondrion seem to be reliant on the charged tRNA import from the cytoplasm for its translation. tRNAs charged with amino acid are shown with aa written in yellow box