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Table 2 Titration of the infectivity of PfCSP/Py Spz through intravenous injection

From: A highly infectious Plasmodium yoelii parasite, bearing Plasmodium falciparum circumsporozoite protein

 

# of Spz injected iv

Day 3 post challengea

Day 4 post challenge

Day 5 post challenge

Wild-type P. yoelii

450

0/5

5/5

5/5

150

0/5

5/5

5/5

50

0/5

4/5

5/5

PfCSP/Py

450

0/5

5/5

5/5

150

0/5

5/5

5/5

50

0/5

5/5

5/5

  1. aNumber of infected mice/number of challenged mice. Infection was defined as the observation of blood stage parasites in thin blood smears by Giemsa staining