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Table 4 Potential antigenic determinants for the Pvs48/45

From: Global genetic diversity of the Plasmodium vivax transmission-blocking vaccine candidate Pvs48/45

# Antigenic region

AA start

AA end

Length

Score

Polymorphism

Sequencea

1

4

19

16

1.235

None

RQLANLLLVLSLLRGI

2

46

64

19

1.083

None

GFKCNFSSKGVHNLEPILT

3

66

90

25

1.197

None

KRSLVCSIYSYFIYDKIKLTIPKKI

4

99

109

11

1.129

None

PEKCFQTVYTN

5

165

189

25

1.206

None

ISNVKGRVALVQVNVLKYPHKITSI

6

220

237

18

1.228

None

GELVVLACEKVDDKCFKK

7

242

304

63

1.154

K250N

SPLSLYKSKKIVYHKNLSIFKAPVYVKSADVTAECSCNVDSTIYTLSLKPVYTKKLIHGCNFS

8

326

341

16

1.138

D335Y

QITCSIELVDTSYNHL

9

347

361

15

1.167

E353Q

PGEVLPECFFQVYQR

10

366

377

12

1.141

A376T

LEPSKIVYLDAQ

11

394

404

11

1.152

None

IVKIFGLVGSI

12

422

447

26

1.255

None

YMSVKIAAGYFGFLAKIFILLIVLLL

  1. aItalics AA indicates Cysteine residues, whereas Bold italics AA represent the location of polymorphic sites