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Table 1 Main characteristics of subjects diagnosed with HMS, immigrants and expatriates

From: Chronic malaria and hyper-reactive malarial splenomegaly: a retrospective study on the largest series observed in a non-endemic country

Characteristic

All

(n = 44)

Expatriates

(n = 36)

Immigrants (n = 8)

p value

Age years; median (IQ range)

56.1 (15.8)

58.6 (10.0)

27.4 (14.2)

0.0001

Gender (F/M)

15/29

10/26

5/3

0.099

Exposure, years; median (IQ range)

20.0 (13.0)

20.0 (12.0)

27.5 (12.0)

0.2278

Presence of symptoms; ratio Y/Na

42/1

34/1

8/0

1.000

Fever; ratio Y/N*

24/19

19/16

5/3

1.000

Asthenia; ratio Y/N*

19/24

18/17

1/7

0.059

Left upper q. pain; ratio Y/Na

9/34

6/29

3/5

0.332

Intestinal discomfort ratio Y/Na

12/31

11/24

1/7

0.407

Spleen diameter in cm; median (IQ range)

18.0 (3.3)

18.0 (3.3)

17.6 (3.5)

0.5643

Hepatomegaly; ratio Y/Na

23/20

21/14

2/6

0.118

Hb, mg/dL normal 12–16; median (IQ range)

10.0 (3.0)

9.6 (2.2)

11.6 (4.0)

0.1695

RBC × 106/µL, n 4.2–5.4; median (IQ range)

3.4 (1.0)

3.3 (0.9)

4.0 (1.1)

0.0239

Plt × 103/µL, n 130–400; median (IQ range)

138.0 (81.0)

128.0 (76.0)

178.5 (100.0)

0.0702

ESR mm/h, n < 25; median (IQ range)

57.5 (43.5)

59.0 (38.0)

51.0 (86.0)

0.7352

IgM, g/L, n < 2.5; median (IQ range)

6.4 (3.9)

6.8 (3.8)

5.0 (12.6)

0.9738

Plasmodium in blood; ratio Y/Nb

22/16

17/15

5/1

0.370

Improved at T1; ratio Y/N

20/2

16/2

4/0

1.000

  1. aInfo on symptoms lacking for one patient
  2. bMalaria search lacking for six patients