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Table 1 Shared 8-mer linear peptidome of rodent and human Plasmodium parasites

From: Defining rules of CD8+ T cell expansion against pre-erythrocytic Plasmodium antigens in sporozoite-immunized mice

Pairing

Stage

Homologous windows (#≥8 aa)

Mean length (aa)

Max length (aa)

Total aa conserved in ≥8 aa windows

% of syntenic proteomea (%)

Py/Pb

All

67,684

25.5

926

1.72 × 106

70.5 % Py/59.3 % Pb

Pf/Pv

All

41,417

15.7

438

6.49 × 105

18.1 % Pf/18.9 % Pv

Py/Pb

Spz

41,424

26.9

926

1.12 × 106

All: 46.5 % Py/38.4 % Pb

Spz: 76.2 % Py/61.6 % Pb

Pf/Pv

Spz

28,793

16.4

438

4.73 × 105

All: 13.2 % Pf/13.8 % Pv

Spz: 20.8 % Pf/13.8 % Pv

Py/Pb

LS

7659

34.8

831

2.67 × 105

All: 10.9 % Py/9.2 % Pb

LS: 79.5 % Py/77.9 % Pb

Pf/Pv

LS

7813

19.3

438

1.51 × 105

All: 4.2 % Pf/4.4 % Pv

LS: 38.6 % Pf/39.3 % Pv

  1. Pb, P. berghei ANKA; Py, P. yoelii 17XNL; Pf, P. falciparum 3D7; Pv, P. vivax Sal1; aa, amino acids
  2. aComparison to all stage or stage-specific syntenic proteomes. Total aa for all stages (Py 2.44 × 106 aa; Pb 2.90 × 106 aa; Pf 3.58 × 106 aa; Pv 3.42 × 106 aa), sporozoite stage (Py 1.46 × 106 aa; Pb 1.81 × 106 aa; Pf 2.27 × 106 aa; Pv 2.19 × 106 aa) and liver stage (Py 3.36 × 105 aa; Pb 3.42 × 105 aa; Pf 3.83 × 105 aa; Pv 3.90 × 105 aa)