Delayed acquisition of Plasmodium falciparum antigen-specific CD4+ T cell responses in HIV-exposed uninfected Malawian children receiving daily cotrimoxazole prophylaxis

Table 1 Demographic characteristics of the study participants

Description^a	Age of study participants at each visit
	6 months			12 months			18 months
	HUU	HEU	p*	HUU	HEU	p	HUU	HEU	p
Demographic data
Number of children per visit	31	33	–	29	31	–	28	30	–
Females (%)	65	46	–	62	42	–	64	40	–
Laboratory parameters
WBC count, ×10³ cells/ml	10.2	9.45	0.51	11.5	12.0	0.65	9.5	8.4	0.34
Total CD4 T cells (%)	58.4	55.2	0.042	51.1	54.8	0.62	48.8	54.8	0.052
Mothers health status
Mother on ART, %	–	97	–	–	100	–	–	97	–
Mother on CTX, %	–	100	–	–	100	–	–	100	–

p p value, WBC white blood cells, ART antiretroviral therapy, CTX cotrimoxazole
* p value obtained with Mann–Whitney U test, p value of <0.05 was considered significant
^aPresented as medians

ISSN: 1475-2875