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Table 4 Hazard ratio of a Plasmodium vivax infection following a previous malaria episode within 90 days of follow-up

From: Declining malaria transmission in rural Amazon: changing epidemiology and challenges to achieve elimination

 

Rate P. vivax episode/100-person-months

Crude HR (95 % CI)

P value

Adjusted HR (95 % CI)

P value

Initial infection

P. falciparum

5.3 (3.2–8.7)

1

 

1

 

P. vivax

11.4 (9.8–12.2)

2.1 (1.2–3.7)

0.009

2.3 (1.3–4.0)

0.006

Mixed Infection

14.2 (9.4–21.6)

2.7 (1.4–5.1)

0.003

2.9 (1.5–5.7)

0.002

Gender

Female

10.5 (8.5–13.0)

1

 

1

0.983

Male

10.8 (9.0–12.9)

1.0 (0.8–1.3)

0.870

1.0 (0.8–1.3)

Age (years)

0–10

10.0 (7.7–13.0)

1

 

1

 

10–20

10.1 (7.5–13.7)

1.0 (0.7–1.6)

0.865

1.1 (0.7–1.5)

0.809

20–40

11.1 (8.5–14.5)

1.1 (0.8–1.6)

0.557

1.2 (0.8–1.8)

0.284

40–60

12.3 (9.0–16.9)

1.2 (0.8–1.8)

0.268

1.3 (0.9–2.0)

0.126

≥60

9.6 (5.4–16.8)

0.9 (0.5–1.7)

0.885

1.0 (0.5–1.7)

0.933

Residence area

Road ranches

8.7 (6.5–11.7)

1

 

1

0.091

Rural settlement

11.4 (9.8–13.3)

1.3 (0.9–1.8)

0.108

1.3 (1.0–1.9)

Season

Rainy

5.9 (4.4–8.0)

1

 

1

<0.001

Dry

13.6 (11.7–15.9)

2.4 (1.7–3.3)

<0.001

2.5 (1.8–3.5)

Use of ITN

No

11.0 (9.2–13.2)

1

 

1

0.284

Yes

10.3 (8.3–12.7)

0.9 (0.7–1.2)

0.564

0.9 (0.7–1.1)