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Table 1 Evolutionary relationship levels of malaria vaccine candidates that have reached clinical trials

From: An evolutionary approach to identify potentially protective B cell epitopes involved in naturally acquired immunity to malaria and the role of EBA-175 in protection amongst denizens of Bolifamba, Cameroon

Level 1

Level 2

Level 3

Level 4

Level 5

Level 6

0

PF3D7_0603400 (TEX1)

0

PF3D7_1216600 (CelTOS)

0

PF3D7_1200600 (VAR2CSA)

 

PF3D7_1133400 (AMA1)

 

PF3D7_1031000 (Pfs25)

 

PF3D7_1035300 (GLURP)

   

PF3D7_1346700 (P48/45)

 

PF3D7_1035400 (MSP3)

   

PF3D7_1335900 (TRAP)

 

PF3D7_1036400 (LSA1)

   

PF3D7_0930300 (MSP1)

 

PF3D7_0206800 (MSP2)

   

PF3D7_0207600 (SERA5)

 

PF3D7_1121600 (EXP1)

   

PF3D7_0404500 (P52)

 

PF3D7_0406200 (Pfs16)

   

PF3D7_0404400 (P36)

 

PF3D7_0102200 (RESA)

   

PF3D7_0304600 (CSP)

 

PF3D7_0702300 (STARP)

   

PF3D7_0731500 (EBA175)

 

PF3D7_0220000 (LSA3)

  1. Levels correspond to phylogenetic relationships defined in Fig. 2. Genes are identified by their official ID number and protein name in parentheses