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Table 1 Median concentrations with 25 and 75 % quartiles indicated for blood parasitaemia and eight soluble markers quantified in the plasma of children with different clinical conditions

From: Plasma levels of eight different mediators and their potential as biomarkers of various clinical malaria conditions in African children

 

Mean ages (in years)

Parasitaemia

levels

Neopterin (ng/ml)

SCD163 (ng/ml)

suPAR (ng/ml)

PTX3 (ng/ml)

sCD14 (ng/ml)

Fractalkine (pg/ml)

sTREM-1 (ng/ml)

MIG (ng/ml)

CTS

 

0

1.93 [1.23–2.61]

236.6 [149.9–327.7]

3.95 [3.26–5.40]

3.21 [2.17–9.37]

2173 [1355–2945]

77.8 [65.5–111.0]

0.45 [0.27–50.2]

1.11 [0.59–1.53]

80 AM

6.3 ± 1.1

765 [58–1614]

3.99 [2.68–4.35]

514.2 [369.30–810.5]

3.72 [3.36–4.35]

0.26 [0.18–1.98]

4245 [2888–6820]

145.8 [109.4–158.0]

0.27 [0.26–0.29]

1.52 [1.41–1.60]

69 UM

2.9 ± 1.7

58,322 [20,656–113,071]

2.56 [2.15–2.98]

529.4 [371.5–910.4]

6.56 [5.58–7.57]

22.92 [8.68–47.40]

11,666 [6918–17,810]

104.3 [93.2–135.2]

0.32 [0.29–0.37]

1.49 [1.40–1.60]

39 UM + 28D

3.1 ± 1.3

0

2.47 [1.10–2.96]

228.5 [185.3–287.3]

6.45 [5.51–7.09]

3.95 [2.12–7.58]

1182 [909–1558]

21.7 [17.6–24.2]

0.39 [0.35–0.45)

0.61 [0.40–0.92]

41 SM

3.0 ± 3.1

14,008 [2317–97,928]

8.63 [8.30–9.03]

385.5 [284.6–503.5]

7.85 [6.07–9.36]

13.69 [5.27–25.27]

2970 [2079–6715]

15.3 [14.4–16.0]

0.52 [0.47–0.60]

1.81 [0.78–3.03]

25 CM

2.4 ± 2.8

100,001 [2062–201,952]

8.20 [7.69–8.83]

360.6 [252.7–470.9]

7.98 [6.93–11.69]

22.20 [8.04–35.12]

1998 [1444–3266]

15.6 [15.0–16.8]

0.50 [0.44–0.58]

2.37 [1.18–3.39]