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Fig. 1 | Malaria Journal

Fig. 1

From: Anti-erythrocyte antibodies may contribute to anaemia in Plasmodium vivax malaria by decreasing red blood cell deformability and increasing erythrophagocytosis

Fig. 1

Associations between antibody responses and clinical status. a The concentrations of total IgG and b the levels of IgG against surface molecules of non-infected red blood cells (nRBCs) were evaluated in sera from healthy individuals (n = 11) and in sera from non-anaemic (n = 119) or anaemic P. vivax-infected patients (n = 11) by sandwich and cell-ELISA, respectively. The results are shown as median values and interquartile ranges. p values were determined using nonparametric tests: a Kruskal–Wallis followed by a post hoc Dunn’s multiple comparison test or b Mann–Whitney test. Asterisks indicate statistically significant difference (p value <0.05). Reactivity index (RI) was calculated as the ratio between the mean OD generated by each duplicate and the mean OD plus three standard deviations of samples from 11 malaria-naïve blood donors never exposed to malaria

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Malaria Journal

ISSN: 1475-2875

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