From: Development of new malaria diagnostics: matching performance and need
Cost per processed sample (USD) | LLOD | Market size | |
---|---|---|---|
Case management | (O): ≤$1.00 (M): ≤$1.00 | (O) < 5 p/µL (elimination) (M) 100–200 p/µL | 171 million slides examined via microscopy [10] |
Parasite screening | (O): ≤$1.00 (M): ≤$5.00 | (O) ≤ 2 p/µLa (M) < 20 p/µL (LAMP, PCR achieve 1–2 p/µL) | ~33 million people (within low-prevalence infection foci. Conservative estimate) [11]. Potential 1.5–8 million tests each year |
Population screening | (O): ≤$1.00 (M): ≤$5.00 | (O) ≤ 2 p/µLa (M) < 20 p/µL (LAMP, PCR achieve 1–2 p/µL) | 7000–10,000 cases surveyed [12] |
Research/drug monitoring | Depends on application | (O) ≤ 5 p/µL (ex: drug trials)a (M) ≤ 5 p/µL (ex: drug trials)a | Approximately 250 TES sites (~50/100 countries actually conducting TES). Numbers for wider research market unclearb |
Microscopy quality control | (O): ≤$1.00 (M): ≤$1.00 | (O): < 10 p/µL (M): 50 p/µL | 29 million slides cross‐checkedc |
Non-endemic countries | (O): ≤$1.00 (M): ≤$5.00 | (O) ≤ 2 p/µLa (M) < 20 p/µL (LAMP, PCR achieve 1–2 p/µL) | 30,000 suspected cases (screens) in USA. 200,000 suspected cases in Western Europed |