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Fig. 1 | Malaria Journal

Fig. 1

From: Comparative pharmacokinetics and pharmacodynamics of intravenous artelinate versus artesunate in uncomplicated Plasmodium coatneyi-infected rhesus monkey model

Fig. 1

Parasite density-time profiles. Parasite density-time profiles of all test monkeys receiving IV AL (blue), IV AS (pink) and control monkeys receiving IM QN (orange) with corresponding color coded arrows indicating dosing time: a IV AL 11.8 mg kg−1 showing eight test monkeys (light blue) and two monkeys that eventually died within 6 h after the first dose (dark blue) and b IV AS 8.0 mg kg−1, in log scale and linear scale in inset. c Mean + 95 % confidence bar in plasma of P. coatneyi infected rhesus monkeys (solid line) including quinine control (dotted line) for each treatment. d Percentage (mean ± 95 % CI) of parasite reduction after treatment

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