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Table 3 Performance RDT and microscopy in mothers and newborns relative to qPCR as gold standard

From: Prevalence and diagnostics of congenital malaria in rural Burundi, a cross-sectional study

 

SD bioline HRPII

Carestart pan-pLDH

Smear

Sensitivity

Specificity

99.3 %

(95 % CI 97.6–99.8)

100 %

(95 % CI 98.3–100)

100 %

95 % CI 98.8–100)

PPV

0.0 %

(95 CI 0.0–84.2)

NPV

100 %

(95 % CI 98.7–100)

100 %

(95 % CI 98.3–100)

100 %

(95 % CI 98.8–100)

  1. Kirundo and Mukenke hospitals, Burundi (March–April 2014)
  2. PPV positive predicted value, NPV negative predicted value, CI confidence interval, SD standard diagnostics, HRPII histidine rich protein, pLDH parasite lactate dehydrogenase