Author, year and country | Epidemiology (baseline parasitemia) | Population coverage/% | Type of study and the context | Anti-malarial(s) | Additional interventions |
---|---|---|---|---|---|
Archibald 1960, Nigeria [45] | 48.7% | 89.7 | Non-RCT Inhabitants of villages in Western Sokoto malaria control campaign | Chloroquine + pyrimethamine |  |
Clyde 1962, Tanzania [46] | 59.8–64% | 95 | Before and after Participants of all ages were recruited | Amodiaquine + primaquine | IRS with DDT |
Roberts 1964a, Kenya [40] | 23% | 95 | Non-RCT Participants of all ages were recruited and were from highlands in Kenya from 2 districts | Pyrimethamine | Â |
Garfield 1983, Nicaragua [27] | 0.42–0.83 cases/1000 population/month | 70 | Before and after (nationwide) Medicine was administered to all persons aged >1 year over 3 days given once to the entire population | Chloroquine + primaquine |  |
Baukapur 1984, India [34] | 0.18/1000 population/month | 76 | Before and after All persons in 2 villages in Valsad District in Gujarat. Migratory population came from malarious areas during study period | Chloroquine | NR |
Pribadi 1986, Indonesia [31] | 13.2% | 93.7 | Before and after Mass chemoprophylaxis among all the individuals in Berakit village | Chloroquine | Â |
Doi 1989b, Indonesia [44] | 30% | 100 | Before and after All aged participants were treated | SPÂ +Â primaquine | NR |
Kaneko 2000, Vanuatu [35] | 62% | 88.3 | Before and after MDA was conducted with all individuals in Aneityum islands | Chloroquine + primaquine + SP |  |
Von Seidlein 2003, Gambia [42] | 41.6% | 85 | RCT/Cluster RCT Individuals older than 6Â months and all non-pregnant women in 9 villages and placebo in other 9 villages | ASÂ +Â SP | Â |
Shekalaghe 2011, Tanzania [12] | 0% by microscope and 2.6% by PCR | 93 | RCT/Cluster RCT Individuals above 1Â year were included. People who had received ACTs in 2Â weeks prior to the study, pregnant women and people with anaemia received different drug regimen. Four each intervention and control randomly assigned | ASÂ +Â SPÂ +Â primaquine | Vector control, larviciding |
Lwin 2015, Thai–Myanmar border [25] | 7.3% by microscopy and 18.4% by uPCR in one study village | 40 | Before and after Study population consisted of all the villagers excluding children <14 years and pregnant women in Thai–Myanmar border | Dihydro-artemesinin + peperaquine | NR |