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Table 4 Studies documenting both community engagement and population coverage (n = 11, in chronological order)

From: Community engagement and population coverage in mass anti-malarial administrations: a systematic literature review

Author, year and country

Epidemiology (baseline parasitemia)

Population coverage/%

Type of study and the context

Anti-malarial(s)

Additional interventions

Archibald 1960, Nigeria [45]

48.7%

89.7

Non-RCT

Inhabitants of villages in Western Sokoto malaria control campaign

Chloroquine + pyrimethamine

 

Clyde 1962, Tanzania [46]

59.8–64%

95

Before and after

Participants of all ages were recruited

Amodiaquine + primaquine

IRS with DDT

Roberts 1964a, Kenya [40]

23%

95

Non-RCT

Participants of all ages were recruited and were from highlands in Kenya from 2 districts

Pyrimethamine

 

Garfield 1983, Nicaragua [27]

0.42–0.83 cases/1000 population/month

70

Before and after (nationwide)

Medicine was administered to all persons aged >1 year over 3 days given once to the entire population

Chloroquine + primaquine

 

Baukapur 1984, India [34]

0.18/1000 population/month

76

Before and after

All persons in 2 villages in Valsad District in Gujarat. Migratory population came from malarious areas during study period

Chloroquine

NR

Pribadi 1986, Indonesia [31]

13.2%

93.7

Before and after

Mass chemoprophylaxis among all the individuals in Berakit village

Chloroquine

 

Doi 1989b, Indonesia [44]

30%

100

Before and after

All aged participants were treated

SP + primaquine

NR

Kaneko 2000, Vanuatu [35]

62%

88.3

Before and after

MDA was conducted with all individuals in Aneityum islands

Chloroquine + primaquine + SP

 

Von Seidlein 2003, Gambia [42]

41.6%

85

RCT/Cluster RCT

Individuals older than 6 months and all non-pregnant women in 9 villages and placebo in other 9 villages

AS + SP

 

Shekalaghe 2011, Tanzania [12]

0% by microscope and 2.6% by PCR

93

RCT/Cluster RCT

Individuals above 1 year were included. People who had received ACTs in 2 weeks prior to the study, pregnant women and people with anaemia received different drug regimen. Four each intervention and control randomly assigned

AS + SP + primaquine

Vector control, larviciding

Lwin 2015, Thai–Myanmar border [25]

7.3% by microscopy and 18.4% by uPCR in one study village

40

Before and after

Study population consisted of all the villagers excluding children <14 years and pregnant women in Thai–Myanmar border

Dihydro-artemesinin + peperaquine

NR