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Fig. 4 | Malaria Journal

Fig. 4

From: A monoclonal antibody-based immunoassay to measure the antibody response against the repeat region of the circumsporozoite protein of Plasmodium falciparum

Fig. 4

Comparison of antibody concentrations in sera from different time points and treatment groups. In both studies sera were obtained after the second (PD2) and third (PD3) vaccine dose and antibody concentrations were measured with R32LR and MAL1C-competition ELISA. In study 1 results obtained in the subjects receiving three doses of RTS,S/AS01 (3xRTS,S/AS01) were compared with those generated in subjects vaccinated with one dose of Ad35.CS.01 followed by two doses of RTS,S/AS01. In study 2, subjects vaccinated with three standard doses of RTS,S/AS01 given with monthly intervals at month 0, 1 and 2 (012) were compared with subjects given a standard dose at months 0 and 1 and 1/5 th of the standard dose at month 5 (017). No significant differences were observed between the study groups or between 2 and 3 vaccine doses

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Malaria Journal

ISSN: 1475-2875

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