Table 2 Potential confounders, factors and covariates expected to have the largest effect on observed insecticide susceptibility
From: Developing global maps of insecticide resistance risk to improve vector control
Variable | Notes |
|---|---|
Sampling bias (spatial) | The dataset was not generated using a single systematic sampling design; the data are highly clustered in geographical space |
Sampling bias (temporal) | The dataset did not come from a time series that sampled the same locations at regular intervals; each time period incorporates a different set of sites and much higher data volumes are available for more recent years |
Species | The full dataset is linked to 74 malaria vector species and species complexes, however, over half of the bioassay records are linked to members of the An. gambiae species complex |
Insecticide | Within each insecticide class, different insecticides were tested (6 carbamates, 5 organochlorines, 16 organophosphates, and 8 pyrethroids) |
Protocol variation | Corrected mortality values were derived from a mixture of WHO bioassays (using 9 updated protocols) and CDC bottle assays |
Exposure dose and duration | The exposure dose and duration used in the bioassays varied although the majority of bioassays used standard doses and times |
Generation tested | Population samples were maintained in the laboratory for differing periods, however, only results from bioassays using F0 and F1 generations were included |