Fig. 1
From: Genome-wide scans for the identification of Plasmodium vivax genes under positive selection
Summary of the SNPs frequency distribution and PCA shows the regional differences. a Frequency distribution of the minor alleles for each of the SNPs scored in a population sample of 6 P. vivax clinical isolates from CMB area. b Distribution numbers of genes (NÂ =Â 4653 analysed in total) with each given number of SNPs in different population. c Principal component analysis based on 133,456 SNPs in CMB isolates and reference strains. The samples are dyed by their geographic origin: blue for Peru and Brazil from South America, green for India from South Asia and grey for Madagascar and Mauritania from Africa, and yellow for Cambodia, North Korean and CMB. The PCA result shows that P. vivax clustered according to their geographic origin. d Three-eigenvector PCA using variation data from CMB isolates and some Asian reference strains. The clinical isolates outside Asia were used as outgroup indicators: Papua New Guinea (PN0046-C), Indonesia (PJ0007-C and PJ0009-C) and Madagascar (M08, M15 and M19). Each isolate is dyed according to its origin and the percentage contribution of each eigenvector is indicated