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Table 4 Odds ratios (and 95% CIs) from mixed-effects logistic regression models for each outcome (seroconversions and seroreversions) on each antibody (AMA-1 and MSP-1)

From: A longitudinal cohort study of malaria exposure and changing serostatus in a malaria endemic area of rural Tanzania

Outcome

Parameter

Seroconversion

Seroreversion

OR (95% CI)

OR (95% CI)

AMA-1

 Year (2013 vs 2012)

3.56 (2.06, 6.15)

0.31 (0.19, 0.53)

 Age (≤20)

0.99 (0.95, 1.04)

1.06 (1.02, 1.10)

 Age (>20)

1.04 (0.97, 1.11)

0.95 (0.90, 1.01)

 Malaria in current year

1.34 (0.70, 2.54)

0.73 (0.28, 1.91)

 Malaria in previous year

2.07 (0.94, 4.56)

0.51 (0.15, 1.71)

 MSP-1 seropositive in current year

2.79 (1.64, 4.76)

0.31 (0.16, 0.58)

 MSP-1 seropositive in previous year

0.25 (0.13, 0.50)

2.01 (1.15, 3.51)

MSP-1

 Year (2013 vs 2012)

2.84 (1.89, 4.25)

0.43 (0.26, 0.79)

 Age (≤20)

0.93 (0.89, 0.97)

1.00 (0.96, 1.05)

 Age (>20)

1.08 (1.02, 1.16)

1.01 (0.95, 1.08)

 Malaria in current year

2.70 (1.65, 4.42)

0.98 (0.45, 2.09)

 Malaria in previous year

0.37 (0.15, 0.95)

1.95 (0.89, 4.25)

 AMA-1 seropositive in current year

3.93 (2.26, 6.81)

0.39 (0.21, 0.71)

 AMA-1 seropositive in previous year

0.50 (0.28, 0.90)

2.58 (1.39, 4.81)

  1. Italicized cells indicate statistical significance