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Table 2 Association between K13 mutations and day 3 parasite positivity

From: Clinical and molecular surveillance of artemisinin resistant falciparum malaria in Myanmar (2009–2013)

K13 mutation

Number of isolates

Total

P

Day 3 negative

Day 3 positive

T474I

2

0

2

1.000

M476V

1

0

1

1.000

C469F

2

4

6

0.004*

N490T

2

1

3

0.365

Y511H

1

0

1

1.000

G533A

4

1

5

0.531

G538V

5

1

6

0.597

N537I

4

5

9

0.004*

P553L

0

1

1

0.140

E556D

1

0

1

1.000

R561H

3

10

13

<0.0001*

P574L

14

5

19

0.166

C580Y

81

24

105

0.004*

F673I

1

3

4

0.010*

A675V

9

0

9

0.621

Total

130

55

185

<0.0001*

  1. * Significantly associated K13 mutation with day 3 parasite positivity after treatment with ACT
  2. Calculated by Chi square test and all other were calculated by Fisher’s exacted test with 95% CIs