Table 1 Summary of discovery miRNAs among patients and animal experimental studies
From: Circulating microRNAs in malaria infection: bench to bedside
Author/(reference) | Year | Study population | Down regulation | Up regulation |
|---|---|---|---|---|
Human specimen | ||||
 Rathjen et al. [55] | 2006 | P.f. parasite in cell culture | miR-451: significantly accumulated in infected RBCs | |
 Xue et al. [50] | 2008 | P.f. infected in human erythroid cells | miR-451, let-7b, miR-16, miR-91, miR-142, miR-144, let-7a, let-7f, miR-92, miR106: identified form infected RBCs | |
 LaMonte et al. [49] | 2012 | HbAS and HbCC RBCs with p. f. | – | miR-451 and miR-223 |
 Chamnanchanunt et al. [63] | 2015 | Patients with p.f. and p.v. infection | miR-451 and miR-16 (plasma of p.v. patients than p.f. patients) | – |
 Chamnanchanunt et al. [64] | 2015 | Patients with malaria infection | miR-451 and miR-16 (RBCs of p.v. patients) | – |
Animal specimen | ||||
 Delic et al. [68] | 2011 | P. chabaudi infected in mice model | miR-10b, let-7a, let-7 g, miR-193a-3p, miR-192, miR-14205p, miR-465d, miR-677, miR-98, miR-694, miR-142-5p, miR-465d, miR-677, miR-98, miR-694, miR-374, miR-450b-5p, miR-464, miR-377, miR-20a, miR-466d-3p: (in liver) | miR-26b, miR-M23-1-5p, miR-1274a: (in liver organ) |
 El-Assaad et al. [69] | 2011 | P. berghei infected in mice model | – | let-7i, miR-27a, miR-150 (in brain organ) |
 Al-Quraishy et al. [67] | 2012 | P. chabaudi infected in mice model | miR-194, miR-192, miR-193A-3P, miR-145, miR-16, miR-99A, miR-99B, miR-15A, miR-152, let-7G, let-7B, miR-455-3P: (in spleen and liver) | – |