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Fig. 2 | Malaria Journal

Fig. 2

From: Immunogenicity of the Plasmodium vivax merozoite surface protein 1 paralog in the induction of naturally acquired antibody and memory B cell responses

Fig. 2

Longevity of the antibody response to the PvMSP1P-19 antigen after recovery from infection. a A survey of antibody responses during the acute phase (n = 40) and after anti-malarial treatment at 3 months (n = 27), 9 months (n = 28) and 12 months (n = 14). The bars represent the mean values. Mann–Whitney U test was used for statistical analysis and P value calculation. The level of significance was set at a P value <0.05. b The stability of the anti-PvMSP1P-19 antibody responses in the same individual (n = 16) during acute phase and at 3-month recovery phase. c A longitudinal cohort analysis of anti-PvMSP1P-19 response persistence in seropositive individuals (n = 5, HR1 = Pv01, HR2 = Pv02, HR3 = Pv03 , LR1 = Pv04, LR2 = Pv05) at their acute phases and by following-up their recovery phases at 3, 9 and 12 months. The dashed line indicates the cut-off value (means ± 2SD of the OD value of malaria-naïve individuals)

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